Giant-Size Spider-Man Vol 1 #1

Plot

Guest-starring Dracula. Aunt May has been stricken by a deadly new strain of the flu for which there is not a vaccine available in the United States. However, a doctor is currently bringing the vaccine to America via ocean liner. Since Aunt May might not have enough time to wait for it, the wall-crawler borrows a skycraft from the Fantastic Four and heads out to sea to retrieve the vaccine. But other people want that vaccine too, namely the Maggia and Dracula! It's a great 3-way battle on-board the S.S. Wendell. (mycomicshop.com)