The Amazing Spider-Man Vol. 2 (1998-2013) #543

Plot

When a nurse at the hospital notices that the elderly gunshot victim in a coma has new substances in her blood (thanks to a transfusion by Peter) and that her niece is paying for her treatment in cash, she contacts the police and lets them know that something fishy is going on; When a detective shows up with some very uncomfortable questions, Peter racks up nine potential felony counts by knocking the cop out and stealing Aunt May away to transfer her to another hospital.